TNF-Α may mediate inflammasome activation in the absence of bacterial infection in more than one way.

Members of the mammalian nucleotide binding domain, leucine-rich repeat (LRR)-containing receptor family of proteins are key modulators of innate immunity regulating inflammation. To date, microbial pathogen-associated molecules and toxins have been identified as key triggers of activation of inflam...

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Autores principales: Susana Álvarez, Ma Ángeles Muñoz-Fernández
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/b7d4965c5a0f413a9ac01cbfd823be8c
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