Cytoplasmic NEAT1 Suppresses AML Stem Cell Self‐Renewal and Leukemogenesis through Inactivation of Wnt Signaling

Abstract As an essential component of paraspeckles, nuclear paraspeckle assembly transcript 1 (NEAT1) localizes in the nucleus, promoting progression of various malignant solid tumors. Herein, an adverse effect of NEAT1 is reported, showing that the short isoform, NEAT1_1 suppresses acute myeloid le...

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Autores principales: Huiwen Yan, Zhi Wang, Yao Sun, Liangding Hu, Pengcheng Bu
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
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Wnt
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Acceso en línea:https://doaj.org/article/b7f2a718550840a79ed60fdfbd44a07e
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