Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

How a precancerous form (dysplasia) becomes gastric cancer is unclear. Here, the authors assess the role of Kras activation in heterogenous dysplastic cells in murine stomach corpus organoids, identifying two dysplastic stem cell populations and show that MEK inhibition causes alterations in cell be...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jimin Min, Paige N. Vega, Amy C. Engevik, Janice A. Williams, Qing Yang, Loraine M. Patterson, Alan J. Simmons, R. Jarrett Bliton, Joshua W. Betts, Ken S. Lau, Scott T. Magness, James R. Goldenring, Eunyoung Choi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/b7f6044c24154289a8aced09b8c59729
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!