Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes

Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes

Abstract Glioblastoma (GBM) is one of the most aggressive types of cancer, which begins within the brain. It is the most invasive type of glioma developed from astrocytes. Until today, Temozolomide (TMZ) is the only standard chemotherapy for patients with GBM. Even though chemotherapy extends the su...

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Bibliographic Details
Main Authors: Ezeddine Harmouch, Joseph Seitlinger, Hassan Chaddad, Geneviève Ubeaud-Sequier, Jochen Barths, Sani Saidu, Laurent Désaubry, Stéphanie Grandemange, Thierry Massfelder, Guy Fuhrmann, Florence Fioretti, Monique Dontenwill, Nadia Benkirane-Jessel, Ysia Idoux-Gillet
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/b7f71d227f1e45b69f1e97f821dc7517
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https://doaj.org/article/b7f71d227f1e45b69f1e97f821dc7517

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