TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration.

Tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4) is frequently overexpressed in carcinomas, suggesting a specific role in cancer. Although TRAF4 protein is predominantly found at tight junctions (TJs) in normal mammary epithelial cells (MECs), it accumulates in the cytoplasm of malig...

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Autores principales: Adrien Rousseau, Alastair G McEwen, Pierre Poussin-Courmontagne, Didier Rognan, Yves Nominé, Marie-Christine Rio, Catherine Tomasetto, Fabien Alpy
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/b8771cce77cd4992a489c9c52e0fecfd
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