Distinct contributions of tensile and shear stress on E-cadherin levels during morphogenesis

The effects of mechanical forces, generated by actomyosin contractility, on E-cadherin based cell adhesion are poorly characterized in vivo. Here, the authors report that normal stress increases E-cadherin levels, whereas shear stress reduces E-Cadherin levels, in the developing Drosophila embryo.

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Auteurs principaux: Girish R. Kale, Xingbo Yang, Jean-Marc Philippe, Madhav Mani, Pierre-François Lenne, Thomas Lecuit
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/b87a16a3ae16427ab429b68ab38c5d05
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