Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus.

Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus.

Most of experiments for HCV infection have been done using lytic infection systems, in which HCV-infected cells inevitably die. Here, to elucidate metabolic alteration in HCV-infected cells in a more stable condition, we established an HCV-persistently-infected cell line, designated as HPI cells. Th...

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Main Authors: Kazuo Sugiyama, Hirotoshi Ebinuma, Nobuhiro Nakamoto, Noriko Sakasegawa, Yuko Murakami, Po-Sung Chu, Shingo Usui, Yuka Ishibashi, Yuko Wakayama, Nobuhito Taniki, Hiroko Murata, Yoshimasa Saito, Masayoshi Fukasawa, Kyoko Saito, Yoshiyuki Yamagishi, Takaji Wakita, Hiroshi Takaku, Toshifumi Hibi, Hidetsugu Saito, Takanori Kanai
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/b88f0306f3f440e2847b7f9c87059aa4
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https://doaj.org/article/b88f0306f3f440e2847b7f9c87059aa4

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