Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus.
Most of experiments for HCV infection have been done using lytic infection systems, in which HCV-infected cells inevitably die. Here, to elucidate metabolic alteration in HCV-infected cells in a more stable condition, we established an HCV-persistently-infected cell line, designated as HPI cells. Th...
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Auteurs principaux: | Kazuo Sugiyama, Hirotoshi Ebinuma, Nobuhiro Nakamoto, Noriko Sakasegawa, Yuko Murakami, Po-Sung Chu, Shingo Usui, Yuka Ishibashi, Yuko Wakayama, Nobuhito Taniki, Hiroko Murata, Yoshimasa Saito, Masayoshi Fukasawa, Kyoko Saito, Yoshiyuki Yamagishi, Takaji Wakita, Hiroshi Takaku, Toshifumi Hibi, Hidetsugu Saito, Takanori Kanai |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2014
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Sujets: | |
Accès en ligne: | https://doaj.org/article/b88f0306f3f440e2847b7f9c87059aa4 |
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