FastClone is a probabilistic tool for deconvoluting tumor heterogeneity in bulk-sequencing samples

Multiple algorithms exist for predicting heterogeneity and clonal architecture from the bulk sequencing of tumor tissue. Here, the authors report on an algorithm, FastClone, which was developed from a DREAM challenge and show that FastClone can accurately predict clonality in simulated data and data...

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Autores principales: Yao Xiao, Xueqing Wang, Hongjiu Zhang, Peter J. Ulintz, Hongyang Li, Yuanfang Guan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b8a8a985e0b94c83996a18132f1a4e60
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