Maintenance and loss of endocytic organelle integrity: mechanisms and implications for antigen cross-presentation

The membranes of endosomes, phagosomes and macropinosomes can become damaged by the physical properties of internalized cargo, by active pathogenic invasion or by cellular processes, including endocytic maturation. Loss of membrane integrity is often deleterious and is, therefore, prevented by mitig...

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Autores principales: Eleanor Childs, Conor M. Henry, Johnathan Canton, Caetano Reis e Sousa
Formato: article
Lenguaje:EN
Publicado: The Royal Society 2021
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Acceso en línea:https://doaj.org/article/b8b323d935d047ccba6ca37209913795
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