Chromosome-level genome assembly of Ophiorrhiza pumila reveals the evolution of camptothecin biosynthesis
Ophiorrhiza pumila is a medicinal plant that can produce the anti-cancer monoterpene indole alkaloid (MIA) camptothecin. Here, the authors report its genome assembly and propose a working model for MIA evolution and biosynthesis through comparative genomics, synteny, and metabolic gene cluster analy...
Guardado en:
Autores principales: | Amit Rai, Hideki Hirakawa, Ryo Nakabayashi, Shinji Kikuchi, Koki Hayashi, Megha Rai, Hiroshi Tsugawa, Taiki Nakaya, Tetsuya Mori, Hideki Nagasaki, Runa Fukushi, Yoko Kusuya, Hiroki Takahashi, Hiroshi Uchiyama, Atsushi Toyoda, Shoko Hikosaka, Eiji Goto, Kazuki Saito, Mami Yamazaki |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b8bd330113a948f992c2712a8064df69 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Organogenesis from leaf and internode explants of Ophiorrhiza prostrata, an anticancer drug (camptothecin) producing plant
por: Shahanaz Beegum,A, et al.
Publicado: (2007) -
The benzylisoquinoline alkaloids, berberine and coptisine, act against camptothecin-resistant topoisomerase I mutants
por: Naomi Inoue, et al.
Publicado: (2021) -
Development and characterization of microsatellite markers in Gaultheria pumila Lf. (Ericaceae)
por: Garcia-Gonzales,Rolando, et al.
Publicado: (2018) -
Screening and selection of camptothecin producing endophytes from Nothapodytes nimmoniana
por: I. A. H. Khwajah Mohinudeen, et al.
Publicado: (2021) -
Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin
por: Judit Huarte, et al.
Publicado: (2021)