Substantial acetylcholine reduction in multiple brain regions of Mecp2-deficient female rats and associated behavioral abnormalities

Rett syndrome (RTT) is a neurodevelopmental disorder with X-linked dominant inheritance caused mainly by mutations in the methyl-CpG-binding protein 2 (MECP2) gene. The effects of various Mecp2 mutations have been extensively assessed in mouse models, but none adequately mimic the symptoms and patho...

Full description

Saved in:
Bibliographic Details
Main Authors: Hiroyasu Murasawa, Hiroyuki Kobayashi, Jun Imai, Takahiko Nagase, Hitomi Soumiya, Hidefumi Fukumitsu
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/b8d2ef6c2414461c99a50d51293eafe9
Tags: Add Tag
No Tags, Be the first to tag this record!