Substantial acetylcholine reduction in multiple brain regions of Mecp2-deficient female rats and associated behavioral abnormalities
Rett syndrome (RTT) is a neurodevelopmental disorder with X-linked dominant inheritance caused mainly by mutations in the methyl-CpG-binding protein 2 (MECP2) gene. The effects of various Mecp2 mutations have been extensively assessed in mouse models, but none adequately mimic the symptoms and patho...
Saved in:
Main Authors: | Hiroyasu Murasawa, Hiroyuki Kobayashi, Jun Imai, Takahiko Nagase, Hitomi Soumiya, Hidefumi Fukumitsu |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/b8d2ef6c2414461c99a50d51293eafe9 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Substantial acetylcholine reduction in multiple brain regions of Mecp2-deficient female rats and associated behavioral abnormalities.
by: Hiroyasu Murasawa, et al.
Published: (2021) -
GABA and glutamate pathways are spatially and developmentally affected in the brain of Mecp2-deficient mice.
by: Rita El-Khoury, et al.
Published: (2014) -
Fluoxetine increases brain MeCP2 immuno-positive cells in a female Mecp2 heterozygous mouse model of Rett syndrome through endogenous serotonin
by: Claudia Villani, et al.
Published: (2021) -
MECP2 regulates cortical plasticity underlying a learned behaviour in adult female mice
by: Keerthi Krishnan, et al.
Published: (2017) -
MeCP2 deficiency exacerbates the neuroinflammatory setting and autoreactive response during an autoimmune challenge
by: M. I. Zalosnik, et al.
Published: (2021)