Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells

Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells

Abstract Epidermal growth factor receptor (EGFR) and activin A are both overexpressed in oral cavity squamous cell carcinoma (OSCC). We evaluated their clinical correlation and activin A-mediated EGFR regulation in this study. Overexpression of both transcripts/proteins indicated a poorer prognosis...

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Bibliographic Details
Main Authors: Chi-Neu Tsai, Chia-Lung Tsai, Jui-Shan Yi, Huang-Kai Kao, Yenlin Huang, Chun-I Wang, Yun-Shien Lee, Kai-Ping Chang
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b8fec2df7ecf4364b817c043c7c50159
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