Prostaglandin E2-EP3 axis in fine-tuning excessive skin inflammation by restricting dendritic cell functions.

Prostaglandin E2 (PGE2) is produced in the skin and is suggested to play a role in the regulation of cutaneous immune homeostasis and responses. However, the multifaceted functions of PGE2 continue to elude our understanding, especially because of the multiplicity of PGE2 receptors--EP1, EP2, EP3, a...

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Autores principales: Noriko Shiraishi, Takashi Nomura, Hideaki Tanizaki, Saeko Nakajima, Shuh Narumiya, Yoshiki Miyachi, Yoshiki Tokura, Kenji Kabashima
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/b938c1fb4df643e4ad15fe2045295303
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