High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation

High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation

Tran et al. combine high throughput sequencing, structural biology and computational simulation to determine the HLA allele and antibody-defined epitope frequencies in renal transplant patients and donors. These results demonstrate the feasibility of HLA epitope matching using data from a national t...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jenny N. Tran, Oliver P. Günther, Karen R. Sherwood, Franz Fenninger, Lenka L. Allan, James Lan, Ruth Sapir-Pichhadze, Rene Duquesnoy, Frans Claas, Steven G. E. Marsh, W. Robert McMaster, Paul A. Keown, Genome Canada Transplant Consortium
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/b93a195a6e5b4de3bc355588fb93e629
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/b93a195a6e5b4de3bc355588fb93e629

Ejemplares similares