High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation

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High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation

Tran et al. combine high throughput sequencing, structural biology and computational simulation to determine the HLA allele and antibody-defined epitope frequencies in renal transplant patients and donors. These results demonstrate the feasibility of HLA epitope matching using data from a national t...

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Detalles Bibliográficos
Autores principales:	Jenny N. Tran, Oliver P. Günther, Karen R. Sherwood, Franz Fenninger, Lenka L. Allan, James Lan, Ruth Sapir-Pichhadze, Rene Duquesnoy, Frans Claas, Steven G. E. Marsh, W. Robert McMaster, Paul A. Keown, Genome Canada Transplant Consortium
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/b93a195a6e5b4de3bc355588fb93e629
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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