Human-Specific Bacterial Pore-Forming Toxins Induce Programmed Necrosis in Erythrocytes
ABSTRACT A subgroup of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins (PFTs) has an unusually narrow host range due to a requirement for binding to human CD59 (hCD59), a glycosylphosphatidylinositol (GPI)-linked complement regulatory molecule. hCD59-specific CDCs are produce...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2014
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| Subjects: | |
| Online Access: | https://doaj.org/article/b94d52502cd64185b0f9e850e20d7be5 |
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