Profile of Basal Cell Carcinoma Mutations and Copy Number Alterations - Focus on Gene-Associated Noncoding Variants

Profile of Basal Cell Carcinoma Mutations and Copy Number Alterations - Focus on Gene-Associated Noncoding Variants

Basal cell carcinoma (BCC) of the skin is the most common cancer in humans, characterized by the highest mutation rate among cancers, and is mostly driven by mutations in genes involved in the hedgehog pathway. To date, almost all BCC genetic studies have focused exclusively on protein-coding sequen...

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Autores principales: Paulina Maria Nawrocka, Paulina Galka-Marciniak, Martyna Olga Urbanek-Trzeciak, Ilamathi M-Thirusenthilarasan, Natalia Szostak, Anna Philips, Laura Susok, Michael Sand, Piotr Kozlowski
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
basal cell carcinoma (BCC)
cancer somatic mutations
noncoding mutations
immune checkpoint
copy number alterations
cancer drivers
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/b95ea444c96542f2b8fe78b2d27006fa
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https://doaj.org/article/b95ea444c96542f2b8fe78b2d27006fa

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