Thy-1+ Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis

Thy-1+ Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis

Abstract Cancer-associated fibroblasts (CAFs) regulate diverse intratumoral biological programs and can promote or inhibit tumorigenesis, but those CAF populations that negatively impact the clinical outcome of lung cancer patients have not been fully elucidated. Because Thy-1 (CD90) marks CAFs that...

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Main Authors: Mark J. Schliekelman, Chad J. Creighton, Brandi N. Baird, Yulong Chen, Priyam Banerjee, Neus Bota-Rabassedas, Young-Ho Ahn, Jonathon D. Roybal, Fengju Chen, Yiqun Zhang, Dhruva K. Mishra, Min P. Kim, Xin Liu, Barbara Mino, Pamela Villalobos, Jaime Rodriguez-Canales, Carmen Behrens, Ignacio I. Wistuba, Samir M. Hanash, Jonathan M. Kurie
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/b98c31b4556442fb996362e7c46fd3c2
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https://doaj.org/article/b98c31b4556442fb996362e7c46fd3c2

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