Rapid Freezing Enables Aminoglycosides To Eradicate Bacterial Persisters via Enhancing Mechanosensitive Channel MscL-Mediated Antibiotic Uptake
ABSTRACT Bacterial persisters exhibit noninherited antibiotic tolerance and are linked to the recalcitrance of bacterial infections. It is very urgent but also challenging to develop antipersister strategies. Here, we report that 10-s freezing with liquid nitrogen dramatically enhances the bacterici...
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Auteurs principaux: | , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2020
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Accès en ligne: | https://doaj.org/article/b99755f767db4afe8339b5daf08bae16 |
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