Viral Characteristics Associated with the Clinical Nonprogressor Phenotype Are Inherited by Viruses from a Cluster of HIV-1 Elite Controllers

Viral Characteristics Associated with the Clinical Nonprogressor Phenotype Are Inherited by Viruses from a Cluster of HIV-1 Elite Controllers

ABSTRACT A small group of HIV-1-infected individuals, called long-term nonprogressors (LTNPs), and in particular a subgroup of LTNPs, elite controllers (LTNP-ECs), display permanent control of viral replication and lack of clinical progression. This control is the result of a complex interaction of...

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Main Authors: Concepción Casado, Sara Marrero-Hernández, Daniel Márquez-Arce, María Pernas, Sílvia Marfil, Ferran Borràs-Grañana, Isabel Olivares, Romina Cabrera-Rodríguez, María-Soledad Valera, Laura de Armas-Rillo, Philippe Lemey, Julià Blanco, Agustín Valenzuela-Fernández, Cecilio Lopez-Galíndez
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
CD4 binding
HIV-1
heritability
LTNP-EC
actin-tubulin modifications
cell signaling
Microbiology
QR1-502
Online Access:https://doaj.org/article/b9c065f676794e36920b4671b9e28c10
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https://doaj.org/article/b9c065f676794e36920b4671b9e28c10

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