The telomere complex and the origin of the cancer stem cell
Abstract Exquisite regulation of telomere length is essential for the preservation of the lifetime function and self-renewal of stem cells. However, multiple oncogenic pathways converge on induction of telomere attrition or telomerase overexpression and these events can by themselves trigger maligna...
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Format: | article |
Langue: | EN |
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BMC
2021
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Accès en ligne: | https://doaj.org/article/b9d99a7caf15421fbad10efff3aadd3b |
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