Resistance to β-lactam antibiotics conferred by point mutations in penicillin-binding proteins PBP3, PBP4 and PBP6 in Salmonella enterica.
Penicillin-binding proteins (PBPs) are enzymes responsible for the polymerization of the glycan strand and the cross-linking between glycan chains as well as the target proteins for β-lactam antibiotics. Mutational alterations in PBPs can confer resistance either by reducing binding of the antibioti...
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Auteurs principaux: | , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2014
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Accès en ligne: | https://doaj.org/article/b9ea03bec44645c79322c48d6b332940 |
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