Sirtuins Are Evolutionarily Conserved Viral Restriction Factors
ABSTRACT The seven human sirtuins are a family of ubiquitously expressed and evolutionarily conserved NAD+-dependent deacylases/mono-ADP ribosyltransferases that regulate numerous cellular and organismal functions, including metabolism, cell cycle, and longevity. Here, we report the discovery that a...
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| Main Authors: | Emre Koyuncu, Hanna G. Budayeva, Yana V. Miteva, Dante P. Ricci, Thomas J. Silhavy, Thomas Shenk, Ileana M. Cristea |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2014
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| Subjects: | |
| Online Access: | https://doaj.org/article/b9ea76d5d00f400d8e2b497edc864f67 |
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