USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response
RAP80 helps to recruit BRCA1 to double-strand breaks, facilitating DNA damage responses. Here the authors report that phosphorylated USP13 deubiquitinates RAP80 after DNA damage, prompting recruitment to the break site.
Enregistré dans:
Auteurs principaux: | , , , , , , , , , |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/b9ff0e1454eb43a897db3dfb43979b21 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|