Conditional deletion of ferritin h in mice reduces B and T lymphocyte populations.

The immune system and iron availability are intimately linked as appropriate iron supply is needed for cell proliferation, while excess iron, as observed in hemochromatosis, may reduce subsets of lymphocytes. We have tested the effects of a ferritin H gene deletion on lymphocytes. Mx-Cre mediated co...

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Autores principales: Liviu Vanoaica, Larry Richman, Maike Jaworski, Deepak Darshan, Sanjiv A Luther, Lukas C Kühn
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/ba2833c096394994b75356945d848b06
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