Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass.

Osteoporosis is a genetic disease characterized by progressive reductions in bone mineral density (BMD) leading to an increased risk of fracture. Over the last decade, genome-wide association studies (GWASs) have identified over 1000 associations for BMD. However, as a phenotype BMD is challenging a...

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Auteurs principaux: Madison L Doolittle, Gina M Calabrese, Larry D Mesner, Dana A Godfrey, Robert D Maynard, Cheryl L Ackert-Bicknell, Charles R Farber
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2020
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Accès en ligne:https://doaj.org/article/ba9084e0cc5e4ca1b66b6852a2ebf052
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