The flavonoid apigenin downregulates CDK1 by directly targeting ribosomal protein S9.

Flavonoids have been reported to inhibit tumor growth by causing cell cycle arrest. However, little is known about the direct targets of flavonoids in tumor growth inhibition. In the present study, we developed a novel method using magnetic FG beads to purify flavonoid-binding proteins, and identifi...

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Auteurs principaux: Yosuke Iizumi, Masakatsu Oishi, Tomoyuki Taniguchi, Wakana Goi, Yoshihiro Sowa, Toshiyuki Sakai
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/ba9f369344d24d1698b1994292a9877e
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