Pch2 orchestrates the meiotic recombination checkpoint from the cytoplasm.
During meiosis, defects in critical events trigger checkpoint activation and restrict cell cycle progression. The budding yeast Pch2 AAA+ ATPase orchestrates the checkpoint response launched by synapsis deficiency; deletion of PCH2 or mutation of the ATPase catalytic sites suppress the meiotic block...
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Auteurs principaux: | Esther Herruzo, Ana Lago-Maciel, Sara Baztán, Beatriz Santos, Jesús A Carballo, Pedro A San-Segundo |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2021
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Accès en ligne: | https://doaj.org/article/bac9f12a83d149aeafe0e4e147a43d54 |
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