Pch2 orchestrates the meiotic recombination checkpoint from the cytoplasm.

During meiosis, defects in critical events trigger checkpoint activation and restrict cell cycle progression. The budding yeast Pch2 AAA+ ATPase orchestrates the checkpoint response launched by synapsis deficiency; deletion of PCH2 or mutation of the ATPase catalytic sites suppress the meiotic block...

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Auteurs principaux: Esther Herruzo, Ana Lago-Maciel, Sara Baztán, Beatriz Santos, Jesús A Carballo, Pedro A San-Segundo
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/bac9f12a83d149aeafe0e4e147a43d54
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