Peptide–oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic

Peptide and oligonucleotide systems are known to self-assemble both in nature and artificial systems. Here, the authors combine both forms of self-assembly through the synthesis of peptideoligonucleotide conjugates and show formation of a three-helix structure that dimerises at higher concentrations...

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Autores principales: Chenguang Lou, Manuel C. Martos-Maldonado, Charlotte S. Madsen, Rasmus P. Thomsen, Søren Roi Midtgaard, Niels Johan Christensen, Jørgen Kjems, Peter W. Thulstrup, Jesper Wengel, Knud J. Jensen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/bacb04f814c143a4bbd60f8011d53d2a
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