Multiple Antitumor Molecular Mechanisms Are Activated by a Fully Synthetic and Stabilized Pharmaceutical Product Delivering the Active Compound Sulforaphane (SFX-01) in Preclinical Model of Human Glioblastoma
Frequent relapses and therapeutic resistance make the management of glioblastoma (GBM, grade IV glioma), extremely difficult. Therefore, it is necessary to develop new pharmacological compounds to be used as a single treatment or in combination with current therapies in order to improve their effect...
Enregistré dans:
Auteurs principaux: | Alessandro Colapietro, Alessandra Rossetti, Andrea Mancini, Stefano Martellucci, Giuseppe Ocone, Fanny Pulcini, Leda Biordi, Loredana Cristiano, Vincenzo Mattei, Simona Delle Monache, Francesco Marampon, Giovanni Luca Gravina, Claudio Festuccia |
---|---|
Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/baf03a3f94c84c318f59603f59efb87f |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Studies on statistical optimization of sulforaphane production from broccoli seed
par: Wu,Yuanfeng, et autres
Publié: (2013) -
Sulforaphane-Mediated Nrf2 Activation Prevents Radiation-Induced Skin Injury through Inhibiting the Oxidative-Stress-Activated DNA Damage and NLRP3 Inflammasome
par: Jinlong Wei, et autres
Publié: (2021) -
A Physiological-Based Model for Simulating the Bioavailability and Kinetics of Sulforaphane from Broccoli Products
par: Quchat Shekarri, et autres
Publié: (2021) -
Protective effects of broccoli extracts and sulforaphane against hydrogen peroxide induced oxidative stress in B16 cells
par: Yao Zhang, et autres
Publié: (2021) -
Sulforaphane Targets TRA-1/GLI Upstream of DAF-16/FOXO to Promote C. elegans Longevity and Healthspan
par: Huihui Ji, et autres
Publié: (2021)