Systemic analysis of gene expression profiles identifies ErbB3 as a potential drug target in pediatric alveolar rhabdomyosarcoma.
Pediatric sarcomas, including rhabdomyosarcomas, Ewing's sarcoma, and osteosarcoma, are aggressive tumors with poor survival rates. To overcome problems associated with nonselectivity of the current therapeutic approaches, targeted therapeutics have been developed. Currently, an increasing numb...
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Auteurs principaux: | Janne Nordberg, John Patrick Mpindi, Kristiina Iljin, Arto Tapio Pulliainen, Markku Kallajoki, Olli Kallioniemi, Klaus Elenius, Varpu Elenius |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/bb05e23f4e6d442f98e303fc92e8b5cc |
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