A more desirable balanced polyunsaturated fatty acid composition achieved by heterologous expression of Δ15/Δ4 desaturases in mammalian cells.

A more desirable balanced polyunsaturated fatty acid composition achieved by heterologous expression of Δ15/Δ4 desaturases in mammalian cells.

Arachidonic (ARA), eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids are the most biologically active polyunsaturated fatty acids, but their biosyntheses in mammals are very limited. The biosynthesis of DHA is the most difficult, because this undergoes the Sprecher pathway--a further elongation...

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Bibliographic Details
Main Authors: Guiming Zhu, Qin Ou, Tao Zhang, Xudong Jiang, Guozhi Sun, Ning Zhang, Kunfu Wang, Heng Fang, Mingfu Wang, Jie Sun, Tangdong Ge
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/bb061e6a47ed4815992ba415297a9465
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