Targeted Amino Acid Substitutions Impair Streptolysin O Toxicity and Group A <italic toggle="yes">Streptococcus</italic> Virulence
ABSTRACT Streptolysin O is a potent pore-forming toxin produced by group A Streptococcus. The aims of the present study were to dissect the relative contributions of different structural domains of the protein to hemolytic activity, to obtain a detoxified form of streptolysin O amenable to human vac...
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2013
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| Accès en ligne: | https://doaj.org/article/bb3003ecff814c90b395fe26d22ddb65 |
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