Human NK cell development requires CD56-mediated motility and formation of the developmental synapse

CD56, a splicing variant of NCAM, marks human NK cell differentiation stages. Here the authors show that developing human NK cells form CD56-enriched synapses with stromal cells, and CD56 is critical to promote motility of NK cells that increases with their maturation.

Saved in:
Bibliographic Details
Main Authors: Emily M. Mace, Justin T. Gunesch, Amera Dixon, Jordan S. Orange
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/bb30adb4b9894421b84506abeafc686a
Tags: Add Tag
No Tags, Be the first to tag this record!