Human NK cell development requires CD56-mediated motility and formation of the developmental synapse

CD56, a splicing variant of NCAM, marks human NK cell differentiation stages. Here the authors show that developing human NK cells form CD56-enriched synapses with stromal cells, and CD56 is critical to promote motility of NK cells that increases with their maturation.

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Autores principales: Emily M. Mace, Justin T. Gunesch, Amera Dixon, Jordan S. Orange
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/bb30adb4b9894421b84506abeafc686a
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