Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins
ABSTRACT The Gram-negative bacterial cell wall component lipopolysaccharide (LPS) is recognized by the noncanonical inflammasome protein caspase-11 in the cytosol of infected host cells and thereby prompts an inflammatory immune response linked to sepsis. Host guanylate binding proteins (GBPs) promo...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2017
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| Accès en ligne: | https://doaj.org/article/bb4d0719860949808c96af8cd370889b |
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