Analysis of Serial Multidrug-Resistant Tuberculosis Strains Causing Treatment Failure and Within-Host Evolution by Whole-Genome Sequencing

Analysis of Serial Multidrug-Resistant Tuberculosis Strains Causing Treatment Failure and Within-Host Evolution by Whole-Genome Sequencing

ABSTRACT The cure rate of multidrug-resistant tuberculosis (MDR-TB) is relatively low in China. The reasons for the treatment failure and within-host evolution during treatment have not been sufficiently studied. All MDR-TB patients receiving standard treatment from January 2014 to September 2016 at...

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Autores principales: Xinchang Chen, Guiqing He, Siran Lin, Shiyong Wang, Feng Sun, Jiazhen Chen, Wenhong Zhang
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
drug resistance
whole-genome sequencing
multidrug-resistant tuberculosis
within-host evolution
treatment outcome
DNA sequencing
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/bb85298d337a4d858958b39f1c292880
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https://doaj.org/article/bb85298d337a4d858958b39f1c292880

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