Generation of germline-competent rat induced pluripotent stem cells.

Generation of germline-competent rat induced pluripotent stem cells.

<h4>Background</h4>Recent progress in rat pluripotent stem cell technology has been remarkable. Particularly salient is the demonstration that embryonic stem cells (ESCs) in the rat (rESCs) can contribute to germline transmission, permitting generation of gene-modified rats as is now don...

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Main Authors: Sanae Hamanaka, Tomoyuki Yamaguchi, Toshihiro Kobayashi, Megumi Kato-Itoh, Satoshi Yamazaki, Hideyuki Sato, Ayumi Umino, Yukiko Wakiyama, Mami Arai, Makoto Sanbo, Masumi Hirabayashi, Hiromitsu Nakauchi
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/bb97da4ca9d24a609a6133340f236fb3
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