Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures.
Environmental exposure to manganese (Mn) leads to a neurodegenerative disease that has shared clinical characteristics with Parkinson's disease (PD). Mn-induced neurotoxicity is time- and dose-dependent, due in part to oxidative stress. We ascertained the molecular targets involved in Mn-induce...
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Auteurs principaux: | , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2014
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Accès en ligne: | https://doaj.org/article/bba6e2a186de4cc785a041da88e5a646 |
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