Organotypic spinal cord cultures: An <em>in vitro</em> 3D model to preliminary screen treatments for spinal muscular atrophy
Spinal muscular atrophy (SMA) is a severe neuromuscular disease affecting children, due to mutation/deletion of survival motor neuron 1 (SMN1) gene. The lack of functional protein SMN determines motor neuron (MN) degeneration and skeletal muscle atrophy, leading to premature death due to respirator...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
PAGEPress Publications
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/bbba8f6e51404cb6b0df6e4954d4f06e |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|