Multivariate meta-analysis reveals global transcriptomic signatures underlying distinct human naive-like pluripotent states.
The ground or naive pluripotent state of human pluripotent stem cells (hPSCs), which was initially established in mouse embryonic stem cells (mESCs), is an emerging and tentative concept. To verify this vital concept in hPSCs, we performed a multivariate meta-analysis of major hPSC datasets via the...
Saved in:
Main Authors: | Kory R Johnson, Barbara S Mallon, Yang C Fann, Kevin G Chen |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/bbc2306d4c814b46a7088f9ea8db8f19 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Direct comparison of distinct naive pluripotent states in human embryonic stem cells
by: S. Warrier, et al.
Published: (2017) -
OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human
by: Xin Huang, et al.
Published: (2021) -
Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation
by: Hemalvi Patani, et al.
Published: (2020) -
Dissection of two routes to naïve pluripotency using different kinase inhibitors
by: Ana Martinez-Val, et al.
Published: (2021) -
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs
by: Yongli Shan, et al.
Published: (2017)