Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B.
<h4>Background</h4>We have previously reported that human recombinant granzyme B (grB) mediates apoptosis in membrane heat shock protein 70 (Hsp70)-positive tumor cells in a perforin-independent manner.<h4>Methodology/principal findings</h4>Optical imaging of uptake kinetics...
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/bbe5931322b0429783f0f82fe2648265 |
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