<italic toggle="yes">N</italic>-Methyl-<sc>d</sc>-Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection

<italic toggle="yes">N</italic>-Methyl-<sc>d</sc>-Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection

ABSTRACT Zika virus (ZIKV) infection is a global health emergency that causes significant neurodegeneration. Neurodegenerative processes may be exacerbated by N-methyl-d-aspartate receptor (NMDAR)-dependent neuronal excitoxicity. Here, we have exploited the hypothesis that ZIKV-induced neurodegenera...

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Autores principales: Vivian V. Costa, Juliana L. Del Sarto, Rebeca F. Rocha, Flavia R. Silva, Juliana G. Doria, Isabella G. Olmo, Rafael E. Marques, Celso M. Queiroz-Junior, Giselle Foureaux, Julia Maria S. Araújo, Allysson Cramer, Ana Luíza C. V. Real, Lucas S. Ribeiro, Silvia I. Sardi, Anderson J. Ferreira, Fabiana S. Machado, Antônio C. de Oliveira, Antônio L. Teixeira, Helder I. Nakaya, Danielle G. Souza, Fabiola M. Ribeiro, Mauro M. Teixeira
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
NMDA receptor
Zika virus
intraocular pressure
memantine
microgliosis
mouse model
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/bbf9d30cd04e4a1ab4713f7591e40595
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https://doaj.org/article/bbf9d30cd04e4a1ab4713f7591e40595

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