Structural insights of human N-acetyltransferase 10 and identification of its potential novel inhibitors

Abstract N-acetyltransferase 10 (NAT10), is an acetyltransferase that regulates RNA stability and translation processes. Association of NAT10 with several diseases including cancer, makes it a promising therapeutic target. Remodelin is the only known NAT10 inhibitor, but the structural information r...

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Autores principales: Mahmood Hassan Dalhat, Hisham N. Altayb, Mohammad Imran Khan, Hani Choudhry
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/bbff75ef64a44c05a77552d24727db64
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