Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting

RNA polymerase I (Pol I) catalyses the transcription of ribosomal RNA precursors, and its transcription initiation mechanism differs from that of Pol II and Pol III. Here the authors present the cryo-EM structure of a trapped early intermediate stage of promoter-recruited Pol I, which reveals the in...

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Autores principales: Michael Pilsl, Christoph Engel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/bc12969f6f034529abea1788d34ac181
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