Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting
RNA polymerase I (Pol I) catalyses the transcription of ribosomal RNA precursors, and its transcription initiation mechanism differs from that of Pol II and Pol III. Here the authors present the cryo-EM structure of a trapped early intermediate stage of promoter-recruited Pol I, which reveals the in...
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Autores principales: | Michael Pilsl, Christoph Engel |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/bc12969f6f034529abea1788d34ac181 |
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