A Serratia marcescens PigP homolog controls prodigiosin biosynthesis, swarming motility and hemolysis and is regulated by cAMP-CRP and HexS.

A Serratia marcescens PigP homolog controls prodigiosin biosynthesis, swarming motility and hemolysis and is regulated by cAMP-CRP and HexS.

Swarming motility and hemolysis are virulence-associated determinants for a wide array of pathogenic bacteria. The broad host-range opportunistic pathogen Serratia marcescens produces serratamolide, a small cyclic amino-lipid, that promotes swarming motility and hemolysis. Serratamolide is negativel...

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Autores principales: Robert M Q Shanks, Roni M Lahr, Nicholas A Stella, Kristin E Arena, Kimberly M Brothers, Daniel H Kwak, Xinyu Liu, Eric J Kalivoda
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/bc2e78af040e482998ea2fa27395c56e
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https://doaj.org/article/bc2e78af040e482998ea2fa27395c56e

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