Cell fate clusters in ICM organoids arise from cell fate heredity and division: a modelling approach

Abstract During the mammalian preimplantation phase, cells undergo two subsequent cell fate decisions. During the first decision, the trophectoderm and the inner cell mass are formed. Subsequently, the inner cell mass segregates into the epiblast and the primitive endoderm. Inner cell mass organoids...

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Bibliographic Details
Main Authors: Tim Liebisch, Armin Drusko, Biena Mathew, Ernst H. K. Stelzer, Sabine C. Fischer, Franziska Matthäus
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/bc322e20319b4056bfa3b840aeedbfc9
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